Comparison the modified Marsh classification, The clinical symptoms and laboratory parameters in coeliac disease (CD)

Background: The incidence of coeliac disease (CD) is increased in the latest years. Patients haven't had serious gastrointestinal symptoms at all and it is diagnosed often delayed. The diagnosis of CD is based on intestinal biopsy evaluated by Marsh classification and presence of antitissue transglutaminase (TTG) antibody. Aim: To compare the symptoms, the laboratory parameters and the pathological description based on Marsh classification. Patients and methods: All patients who were diagnosed by histopatology classified mucosal mild (Marsh3a), moderate (Marsh3b) or complete (Marsh3c) atrophy of villi. This stag…