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Changes in haemostatic parameters induced by drospirenone-containing oral contraceptives

SN Tchaikovski, MCLGD Thomassen, SD Costa, C Brandkvist, K Bremme, J Rosing · Geburtshilfe und Frauenheilkunde · 2011 · Heft 08

Dokument
1079338
CareLit-ID
Jahr
2011
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
SN Tchaikovski, MCLGD Thomassen, SD Costa, C Brandkvist, K Bremme, J Rosing
Ausgabe
Heft 08 / 2011
Seiten
–
Erschienen: 2011-08-30 00:00:00
ISSN
0016-5751
DOI
10.1055/s-0031-1286406

Zusammenfassung

Introduction: Oral contraceptives (OC) increase the risk of venous thrombosis. The thrombosis risk is dependent on the OC formulation and may be explained by an increased endogenous thrombin potential and acquired resistance to activated protein C (APC). There is limited information on the effect of OC, containing one of the newest progestogen-compounds drospirenone (DRSP-OC) on the endogenous thrombin potential and APC resistance. Methods: In a study population consisting of 14 healthy women between 21 and 33 years of age we investigated the effect of DRSP-OC on thrombin generation, APC resistance, the function…

Schlagworte

Geburtshilfe und Frauenheilkunde