Female genital malformations: new hypothesis about embryo-morphogenesis

The famous german scientific professor Johannes Peter Muller suggested embryological theory about utero-vaginal morphogenesis 150 year ago, by investigation human emryos with simple light microscopy devices. According original Mullerian theory: Fallopian tubes, Uterus and Vagina formes by fusion of pair paramesonephral (Mullerian) ducts, so Vestibulum vaginae derivates from Sinus Urogenitalis [Muller I.P. Anatomie des Menschen, 1931, Berlin, p.272–275]. Mesonephral ducts completely reduced in female embryos, but derivates ductus seminipherus in male embryos. Embryological investigations now made on laboratory ra…