Bariatric surgery ameliorates NAFLD in morbidly obese patients
A Kahraman, M Pronadl, M Schlattjan, A Wree, T Al-Malat, A Altinbas, LP Bechmann, G Gerken, A Canbay · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: In western countries the most common liver disease is Non-alcoholic fatty liver disease (NAFLD). In the present study the effects of weight loss on liver injury, markers of hepatocyte apoptosis and cytokines were analysed 4 weeks and 6 months after bariatric surgery in a cohort of obese NAFLD patients. Methods: Blood and liver tissue were retrieved from 79 morbidly obese patients during the bariatric surgery, at week 4 and 6 months after the procedure. 44 patients (37f/7m, mean age 40.3±8.3 y) underwent Roux-en-Y gastric bypass (RYGB) and 35 patients (24f/11m, mean age 47.2±9.4 y) underwent sleeve gastrect…