CareLit Fachartikel
Altered antigen presentation properties of macrophages during the allergic airway inflammation
C Winkler, H Carstens, L Witte, M Müller, JM Hohlfeld · Pneumologie · 2011 · Heft 12
Dokument
1079520
CareLit-ID
Jahr
2011
Publikation
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Metadaten
DOI
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Zusammenfassung
Introduction: Alveolar Macrophages (AMΦ) play an important role in the innate and adaptive immune response of the lung. During pulmonary infection and allergic airway inflammation AMΦ can be activated and polarized. The alternatively activated phenotype (aaMΦ) is induced by interleukin (IL)-4, a cytokine which is present during an allergic airway inflammation. However, the functional role of aaMΦ during an allergic airway inflammation is poorly understood. Thus, we characterized aaMΦ with regard to the adaptive immune response underlying the inflammation. Methods: Murine bone marrow derived macrophages (BMDMs) w…
Schlagworte
Antigen Presentation
After
Bronchoalveolar Lavage
Allergens
Cytokine
Asthma
Blood
Pneumologie
