CareLit Fachartikel
Selective Glucocorticoid Receptor Agonists for Treatment of Inflammatory Bowel Disease – in vitro studies
Kerstin C. Reuter, Stefan M. Loitsch, Axel M. Dignass, Jürgen Stein · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Dokument
1079658
CareLit-ID
Jahr
2012
Publikation
PDF
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
The mucosal lining of the intestine constitutes a barrier between the luminal environment and the mucosal immune system. In the course of IBD, damage and impairment of the intestinal epithelial surface are frequently observed resulting in systemic penetration of detrimental substances, leading to a generalized immune response and inflammation. Thus, disease remission requires repair of the damaged epithelium and disappearance of inflammation to restore normal homeostasis of the host [1,2]. Glucocorticoids (GC's), such as Dexamethasone (Dex), are successfully used in the treatment of acute inflammatory bowel dise…
Schlagworte
Cytokines
Cytokine
After
Dexamethasone
Budesonide
Zeitschrift für Gastroenterologie
