Postoperative Ableitungen von Lokalen Feldpotentialen bei Patienten mit Bewegungsstörungen

Deep brain stimulation (DBS) has become an established treatment in patients with movement disorders. However, the exact mechanism of action is still not completely understood. Functional neurosurgery has provided the unique opportunity to directly record neuronal activity from deep brain structures. In my talk I will present data from local field potential recordings in patients undergoing DBS for Parkinson's disease, dystonia and Tourette syndrome to show that abnormal oscillatory activity can be found in the cortex–basal ganglia loop in those patients. This abnormal activity is disease-specific, it is correla…