Reduced activation of brain networks underlying theory of mind is associated with treatment outcome in juvenile anorexia nervosa
M Schulte-Rüther, V Mainz, GR Fink, B Herpertz-Dahlmann, K Konrad · Klinische Neurophysiologie · 2012 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective: Converging evidence suggests an impairment of social functioning in patients with anorexia nervosa (AN) which might be associated with long-term outcome. Recent behavioral studies have found deficits in theory of mind (ToM), the ability to understand the mental states of other people, in patients with AN. The present study aimed at elucidating the neural mechanisms underlying ToM-deficits in AN. Method: 19 adolescent patients with AN and 21 age-matched controls were investigated using functional magnetic resonance imaging upon admission to hospital (T1) and at discharge from hospital after weight reco…