Diagnostic accuracy of noninvasive fecal markers in ulcerative colitis
A Annaházi, T Molnár, K Farkas, A Rosztóczy, F Izbéki, K Gecse, O Inczefi, F Nagy, I Földesi, M Szűcs, L Ferrier, V Theodorou, L Bueno, T Wittmann, R Róka · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Colonoscopy is the gold standard in the diagnosis and follow-up of ulcerative colitis (UC), however, it is invasive, costly and uncomfortable for the patient. In the last decades non-invasive markers, such as CRP or fecal calprotectin have been challenged to replace endoscopic evaluation of disease activity and mucosal lesions. Additionally, matrix-metalloprotease 9 (MMP-9) has been suggested as a predictor of UC in the urine of children with low specificity, but fecal MMP-9 levels have never been measured. Aims: Our aims were: (i) to compare the diagnostic accuracy of fecal calprotectin in compariso…
