Severe course of Hepatitis E Virus infection in a patient with pre-existing autoimmune liver disease

Hepatitis E virus (HEV) infection has been considered to be a travel-associated, self-limiting disease. In recent years sporadic cases of acute hepatitis E virus (HEV) infections have been described in industrialized countries, and the number of documented autochthonous infections seems to be increasing. In pregnant women and patients with liver disease HEV can lead to fulminant hepatic failure. HEV has also been described as a cause of chronic hepatitis in immunocompromised patients. We here report a severe case of HEV infection in a 50-year-old male patient. He presented to our hospital with fatigue, loss of a…