Enhanced Liver Fibrosis (ELF) score is related to liver dysfunction and predicts mortality in cirrhosis

Background: The Enhanced liver fibrosis (ELF) test is a noninvasive fibrosis panel composed of hyaluronic acid (HA), procollagen-3 N-terminal peptide (P3NP), and tissue inhibitor of metalloproteinase-1 (TIMP1). Previous studies have established high diagnostic accuracy of the ELF score to assess hepatic fibrosis and to predict liver-related clinical outcomes in chronic viral hepatitis and fatty liver disease. Aim of the present study was to relate baseline ELF scores to mortality in a cohort of cirrhotic patients. Methods: We enrolled 63 consecutive cirrhotic patients admitted to our outpatient liver clinic (29%…