CareLit Fachartikel

CapG a putative oncogen is involved in invasiveness of breast cancer cells

M Neumann, RP Neves, B Betz, C Schleithoff, T Kaleta, M Fleisch, T Fehm, D Niederacher · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2013 · Heft 06

Dokument
1081535
CareLit-ID
Jahr
2013
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Senologie - Zeitschrift für Mammadiagnostik und -therapie
Autor:innen
M Neumann, RP Neves, B Betz, C Schleithoff, T Kaleta, M Fleisch, T Fehm, D Niederacher
Ausgabe
Heft 06 / 2013
Seiten
–
Erschienen: 2013-06-04 00:00:00
ISSN
1611-6453
DOI
10.1055/s-0033-1347646

Zusammenfassung

Objective: The aim of this work was to study the correlation between CapG-expression level and clinico-pathological parameter in breast cancer as well as functional characterization of CapG and analysis of CapG-transcriptome in mamma carcinoma cell lines to understand the pathogenic mechanism of CapG upregulation. Material and Methods: CapG expression level in breast cancer tissue of 78 patients was analyzed by qRT-PCR on an ALF-sequencer. For CapG-expression levels in MaCa-cell lines qPCR with relative quantification was used. Statistical significance was calculated using chi2 test or fisher's test, respectivel…

Schlagworte

Breast Work After Senologie - Zeitschrift für Mammadiagnostik und -therapie