Relapse management in patients with GHB dependence

Einleitung: Gamma-hydroxybutyrate (GHB) is a (GABA metabolite and agonist with central nervous depressive activity. GHB addiction is a rapid growing problem in the Netherlands. New and efficient methods for detoxification from GHB have been developed. However, after detoxification patients suffer from severe craving leading to rapid relapse in substance abuse mainly GHB. Relapse in detoxified patients is alarmingly high. Methods to provide the best treatment for the addicted patients are limited. This study presents preliminary data about the effect of Baclofen in relapse management. Methode: Open label design m…