Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis
F Finkelmeier, V Köberle, J Bojunga, B Kronenberger, S Zeuzem, J Trojan, A Piiper, O Waidmann · Zeitschrift für Gastroenterologie · 2014 · Heft 01
Bibliografische Angaben
Zusammenfassung
Objective: Vitamin D is involved in many biological functions such as proliferation, apoptosis, cellular signaling and anti-inflammation. It has been identified as prognostic factor in malignant and non-malignant diseases and it is even considered as potential treatment option in multiple cancers. However, the role of vitamin D in HCC as a prognostic factor remains inconclusive. Therefore, we performed a prospective cohort study to investigate the relation of vitamin D levels to stage and the prognosis of HCC patients. Methods: From February 2009 to July 2013, 200 patients with the diagnosis of HCC presenting at…
