Cardiac function and pulmonary vasoreactivity to maternal hyperoxygenation (MH) in fetuses with Hypoplastic Left Heart (HLH)

Objective: Prospective analysis of RV function in fetuses with HLH compared to normal fetuses. In addition firstly to describe the response of fetal lung vasculature to MH in case of prenatally diagnosed HLH, secondly to evaluate the ability of MH to differentiate between newborns with HLH without need for immediate atrial septostomy and newborns who will undergo immediate left atrial septoplasty after birth, thirdly to compare these data with pulmonary venous Doppler flow spectra and 2-D evaluation of the interatrial communication in case of HLH. Methods: Cross-sectional prospective study of fetuses ≥26 weeks o…