Symptom assessment by means of the COPD-Assessment Test (CAT) in patients treated with Roflumilast: the DINO study (Daxas in COPD therapy)

Background Improving quality of life (QoL) and reducing the COPD-related symptoms are an important part of COPD management. This single-arm, non-interventional study investigated the effects of add-on roflumilast on patients' health status and symptoms in routine clinical practice by using the COPD Assessment TestTM (CAT) and a COPD symptom scale. Methods According to labelling, a total of 5,375 COPD patients (intention-to-treat, ITT) were treated with roflumilast 500 µg for up to 6 months. This study was performed at 2195 sites in Germany. CAT scores were measured at study start (V1), after 3 (V2) and 6 months…