Magnetic hyperthermia – high therapeutic efficiency of superparamagentic iron oxide nanoparticles in cancer xenograft models
H Dähring, R Lundwig, S Kossatz, V Ettelt, G Rimkus, I Hilger, M Marciello, G Salas, V Patel, FJ Teran · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2014 · Heft 04
Bibliografische Angaben
Zusammenfassung
Zielsetzung: Magnetic fluid hyperthermia (MFH) is a promising method for the minimal invasive treatment of tumors. However, optimized nanomaterials to supply thermal stress inside the tumor remain to be identified. The present study investigates the therapeutic effects of magnetic hyperthermia induced by superparamagnetic iron oxide nanoparticles in two xenograft- models. Material und Methodik: Two different magnetic nanoparticles, synthesized via an aqueous (12 nm core size) and an organic route (15 nm core size) were analyzed in terms of their specific absorption rate (SAR), cell uptake and their effectively i…
