Association between subclinical inflammation and painful polyneuropathy in an older population: KORA F4 study
C Herder, BWC Bongaerts, W Rathmann, M Heier, B Kowall, W Koenig, B Thorand, M Roden, C Meisinger, D Ziegler · Diabetologie und Stoffwechsel · 2014 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Inflammatory processes have been implicated in the pathogenesis of painful distal sensorimotor polyneuropathy (DSPN). However, the relationship between inflammatory biomarkers and painful DSPN has not been assessed in population-based studies. Therefore, we investigated whether circulating levels of seven pro- and anti-inflammatory immune mediators were associated with painful DSPN in older individuals of the general population. Methods: Among 1047 participants aged 61 – 82 years from the KORA F4 study, 391 were affected by DSPN. DSPN was defined by a Michigan Neuropathy Screening Instrument (MNSI) s…
