Is the tuberculin skin test alone accurate in moderate-to-severe BCG vaccinated patients with inflammatory bowel disease treated with immunosuppressives to test for latent tubercu…
K Gecse, Z Kürti, B Lovász, Á Szabó, M Mandel, A Gyurcsányi, K Kristóf, Z Végh, A Mohás, B Csákó, L Kiss, P Golovics, P Lakatos · Zeitschrift für Gastroenterologie · 2014 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and Aims: There are few data available on effect of immunomodulator/biological therapy on the accuracy of tuberculin skin test (TST, Mantoux skin test) and interferon-gamma release assay (IGRA) in BCG vaccinated immunosuppressed IBD patients. Our aim was to define the accuracy of the TST and IGRA tests in a BCG vaccinated referral IBD cohort treated with immunosuppressives and/or biologicals. Patients and Methods: Data of 90 consecutive moderate-to-severe IBD (77 CD, 13 UC) patients were analyzed (male/female: 42/48, median age at diagnosis: 23.0; SD: 10.02 years, duration: 7.0; SD:6.1 years). Patient…
