Update of single institution experiences with intraoperative radiotherapy (IORT) in targeted oncoplastic breast surgery

Background: Breast-conserving surgery (BCS) is performed in an oncoplastic approach with tumor-specific immediate reconstruction of the partial mastectomy defect. In the attempt to further improve local outcome in breast-conserving therapy we introduced intraoperative radiotherapy (IORT) with low-kilovoltage X-rays as a boost during oncoplastic BCS followed by EBRT Material and Methods: Between February 2010 and July 2012, a total of 149 patients were treated with IORT as a boost during primary oncoplastic breast-conserving surgery, followed by whole-breast radiotherapy. After segmental resection of the tumour d…