Gastric bypass improves glycemic control and reduces systemic inflammation in non-severely obese patients (BMI < 35 kg/m2) with type 2 diabetes mellitus
A Billeter, S Vittas, B Israel, T Schulte, MW Büchler, A Hidmark, TH Fleming, BP Müller, PP Nawroth · Diabetologie und Stoffwechsel · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Bariatric surgery has been shown to improve type 2 diabetes mellitus (T2DM) in obese patients. Based on these findings, the ability of Roux-en-Y gastric bypass (RYGB) to improve glycemic control in non-severely obese patients and the effects on systemic cytokine levels were investigated. Methods: Twenty consecutive patients with a body mass index (BMI) between 25 – 35 kg/m2 and a poorly controlled, insulin-dependent T2DM were enrolled. All patients were treated with a standardized RYGB. Parameters of glycemic control, serum and isolated circulating monocytes were collected over 24 months. Cytokines…
