Nipple Aspirate Fluid (NAF) cytology supports prediction of breast cancer risk using the IBIS model
J Kylstra, M Kalnoski, T Vo, S Quay · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction Ductal Hyperplasia is part of most breast cancer predictive algorithms including IBIS, conferring a 1.9 – 4.2 fold risk increase for resp. benign- and atypical hyperplasia. However, absent of prior biopsy, information on ductal pathology is usually absent, leading to underestimation of BCa risk. We explored the contribution of ductal pathology information to IBIS' ability to classify women to risk groups. Methods. IBIS risk factors were recorded from women w/o prior history of BCa during routine annual exams. To assess hyperplasia, NAF was collected with the ForeCYTE Breast Aspirator. Cytology was g…