CareLit Fachartikel
Multiscale modelling of vascular dependent tumor growth in hepatocellular carcinoma (HCC) under therapy with transarterial chemoembolization (TACE)
H Perfahl, M Horger, N Malek, M Reuss, M Bitzer · Zeitschrift für Gastroenterologie · 2015 · Heft 08
Dokument
1084523
CareLit-ID
Jahr
2015
Publikation
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
Background and Aims: TACE is an established option in advanced HCC. Despite complete disruption of blood flow by imaging, a distinct number of tumor cells survive that are responsible for tumor regrowth. To investigate the influence of different parameters that determine TACE efficacy, a multiscale model was developed to study the evolution of vascular supply and angiogenesis. This mathematical model is informed, parameterized and directly validated using clinical data, based on 43 patients. The aim was to get new hypothesis to improve the efficacy of TACE. Methods: Development of a 3-dimensional multiscale mode…
Schlagworte
Tumor
Blood
After
Blood Vessels
Movement
Zeitschrift für Gastroenterologie
