Handling of complex data in gastroenterology: Multi-step clustering of preclinical data on a combination phytomedicine, STW 5
G Lorkowski, O Kelber, H Abdel-Aziz, K Nieber, M Storr · Zeitschrift für Gastroenterologie · 2015 · Heft 08
Bibliografische Angaben
Zusammenfassung
Introduction: In functional gastrointestinal diseases (FGDs), a multitude of concomitant causes and likewise also targets for therapeutic interventions have been identified (Allescher 2006). Therefore, a multi-target approach is a promising therapeutic strategy, as is exemplified by STW 5, a fixed combination herbal medicinal product of nine herbal extracts (Ottillinger et al. 2013). To allow an overview of targets addressed by STW 5 and the role of its components in relation to the different forms and causes of functional GI diseases, an evaluation of the data, which have been gained from more than 100 pharmaco…