Combining the advantages of CellSearch and CellCelector enables the characterization of circulating tumor cells
M Neumann, S Schömer, Y Decker, H Schneck, R Neves, L Brandi, N Stoecklein, T Fehm, F Meier-Stiegen, H Neubauer, D Niederacher · Geburtshilfe und Frauenheilkunde · 2015 · Heft 08
Bibliografische Angaben
Zusammenfassung
Circulating tumor cells (CTC) are rare cells and dissociated successfully from the primary tumor into the blood stream. Only a small proportion is capable to extravasate and form metastases. However, the presence of CTCs is associated with increased risk to develop metastases and therefore a short survival. Understanding the heterologous CTC biology enables the choice of the optimal therapy and improves the prognosis. For this, detection and isolation of CTCs is necessary. Here we show a workflow to characterize CTCs by combining the advantages of both the CellSearch®- and CellCelector™-System. Single cells were…
