Vaginal progesterone combined with cervical pessary – a further chance for pregnancies at risk for spontaneous preterm birth?

Objective: The aim of this pilot study was to evaluate whether vaginal progesterone (VP) improves the effect of cervical pessary (CP) when added in singleton pregnancies with short cervical length (CL). Methods: Up to 2011, a CP was the standard procedure to treat risk patients with a history of spontaneous preterm birth (SPB) and/or conization with a CL < 10th centile and screening patients with a CL< 3 rd centile with a CP. After the publication of Hassan et al. (2011), 200 mg VP were additionally applied in these patients (CPVP). Risk patients (n = 55) were treated from the 1st trimester onwards, patients of…