The first human uterus allograft from a cadaveric donor

Transplantation of a uterus into a woman with absolute uterine-related infertility could be a real solution. We transplanted the uterus of a brain-dead woman into a patient of 21 with Rokitansky-Kuster-Hauser syndrome. Transplantation consisted of revascularisation of the right and left hypogastric vessels, orthotopic positioning of the uterus, connection of the transplanted vaginal extension to the neovaginal (previously reconstructed with intestine) vault and fixation of all necessary supplementary ligaments to provide a stable structure. Immunosuppressive treatment was administered with antithymocyte globulin…