CareLit Fachartikel

External muscle stimulation differentiates circulating hematopoietic stem cells in diabetes patients

I Spanidis, A Hidmark, T Fleming, N Volk, V Eckstein, JB Gröner, S Kopf, PP Nawroth, D Oikonomou · Diabetologie und Stoffwechsel · 2016 · Heft 04

Dokument
1084916
CareLit-ID
Jahr
2016
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
I Spanidis, A Hidmark, T Fleming, N Volk, V Eckstein, JB Gröner, S Kopf, PP Nawroth, D Oikonomou
Ausgabe
Heft 04 / 2016
Seiten
–
Erschienen: 2016-04-19 00:00:00
ISSN
1861-9002

Zusammenfassung

Introduction: External electric muscle stimulation (EMS) can reduce pain resulting from diabetic neuropathy (DN), a vascular complication of diabetes. It was hypothesized that EMS-treatment activated circulating CD34+ hematopoietic stem cells (HSC), which can participate in vessel repair by differentiating into endothelial progenitor cells (EPC). Methods: 24 DN patients were evaluated for neuropathic symptoms using Diabetic Neuropathy Symptom Score (NSS) and Neuropathy Disability Score (NDS) after three 60 minutes EMS-treatments. The frequency of CD34+ HCS and expression of surface markers were determined by flo…

Schlagworte

Diabetologie und Stoffwechsel