The effect of lifestyle intervention in severely obese subjects on the soluble form of Activated Leukocyte Cell Adhesion Molecule (ALCAM)
A Sulaj, J Zemva, U Zech, A Woehning, M Brune, G Rudofsky, P Nawroth, T Fleming, R von Bauer · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction/Background: Activated leukocyte cell adhesion molecule (ALCAM) functions as a pattern recognition receptor and its soluble form, sALCAM, is involved in ALCAM-dependent and -independent immune mechanism(s). The aim of this study was to investigate the effect of a lifestyle intervention in obesity on sALCAM serum concentration and its association with metabolic parameters. Methods: Thirty severely obese subjects were randomly selected from the OPTIFAST®52 program. This program was divided for the purpose of this study into 2 crucial phases: an initial 12-week active weight reduction phase, followed by…
