Value of transient elastography (Fibroscan®) in patients with autoimmune hepatitis on immunosuppressive treatment

Background: Autoimmune hepatitis (AIH) is characterized by elevated immunoglobulin G (IgG), presence of autoantibodies and inflammation of the liver leading to fibrosis and cirrhosis. Immunosuppressive treatment improves liver function tests, ameliorates symptoms and prolongs survival. Moreover, regression of fibrosis during immunosuppressive treatment has been demonstrated. However, the value of non-invasive measurement of fibrosis by transient elastography (TE, Fibroscan®, Echosens, France) during treatment of AIH is not established. Methods: Fibrosis was staged according to Ludwig score on a four-point scale…