Cell death biomarkers are associated with development of hepatorenal syndrome as well as response to terlipressin therapy
M Nguyen-Tat, T Austgen, V Sivanathan, J Ahrens, D Sollinger, J Rey, M Wörns, P Galle, J Marquardt · Zeitschrift für Gastroenterologie · 2016 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background and aim: Hepatorenal syndrome (HRS) is a severe complication of patients with liver cirrhosis and associated with high mortality rates if left untreated. Levels of cell death parameters are significantly elevated in patients with acute and chronic liver diseases. However, the role of these markers in patients with HRS is unknown. Aim of the study was to investigate if serum levels of M30 and M65 correlate with the risk of HRS development in cirrhotic patients and clinical outcome of HRS. Methods: Between April 2013 and July 2015, clinical relevant parameters from from patients with liver cirrhosis wit…