Is CEUS a tool in a beginner's hand? How much a CAD prototype and a pseudocoloring pattern can help in characterizing the malignancy of FLL?

Background and aim: CEUS improved the characterization of focal liver lesions (FLLs), but is an operator-dependent method. The goal of this paper was to test a computer assisted diagnosis (CAD) prototype and to see its benefit in assisting a beginner in evaluation of FLLs. Material and method: 97 good quality CEUS videos [34% hepatocellular carcinomas (HCC), 12.3% hypervascular metastases (HiperM), 11.3% hypovascular metastases (HipoM), 24.7% hemangiomas (HMG), 17.5% focal nodular hyperplasia (FNH)] were used to develop a CAD prototype based on an algorithm that tested a binary decision based classifier and a ps…