Fatal neonatal hemochromatosis as a rare cause of intrauterine growth restriction
U Schneider, I Muth, T Wieland, C Voigt, C Doerfel, M Gajda, HJ Mentzel, H Proquitte · Ultraschall in der Medizin - European Journal of Ultrasound · 2016 · Heft 08
Bibliografische Angaben
Zusammenfassung
Neonatal hemochromoatosis (NHC) is characterized by severe liver disease in the newborn accompanied by extrahepatic siderosis. This Gestational Alloimmunic Liver Disease (GALD) is resulting from the placental transfer of maternal IgG antibodies against fetal hepatocytes. Diagnosis is often only made post mortem for the severe and unexpected occurrence [1]. A 27 y east-african patient (GIII/PII, 2 healthy children born at term in 2003/SVD and 2012/CS for cephalopelvic disproportion) was admitted for anhydramnios and symmetric IUGR (EFW 1020 g/< 3rd perc.) at 31+0 wksGA. PROM could be excluded biochemically; sonog…
