CareLit Fachartikel

Treatment of Multisystem Langerhans Cell Histiocytosis. Results of the DAL-HX 83 and DAL-HX 90 Studies

M. Minkov, N. Grois, A. Heitger, U. Pötschger, T. Westermeier, H. Gadner · Klinische Pädiatrie · 2000 · Heft 04 · S. 139-144

Dokument
1099310
CareLit-ID
Jahr
2000
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
M. Minkov, N. Grois, A. Heitger, U. Pötschger, T. Westermeier, H. Gadner
Ausgabe
Heft 04 / 2000
Jahrgang 212
Seiten
139-144
Erschienen: 2000-01-01 00:00:00
ISSN
0300-8630

Zusammenfassung

Summary. BACKGROUND: The prognosis of children with multisystem Langerhans cell histiocytosis (LCH) has improved with the application of chemotherapy. However, treatment strategies used varied from conservative approach with treatment only during disease exacerbation to intensive chemotherapy starting immediately after diagnosis. No single drug or regimen has been proven to be superior to the others. Thus, optimal treatment of multisystem LCH remains still an unsolved problem. PATIENTS: Three hundred and twenty-four patients enrolled in the DAL-HX 83 and DAL-HX 90 studies were retrospectively re-evaluated by usi…

Schlagworte

Langerhans cell histiocytosis therapy treatment prognosis survival Langerhanszell-Histiozytose Therapie Behandlung Prognose Überleben Diagnosis After Observation Mercaptopurine Blood Klinische Pädiatrie