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Gemcitabine-Containing Chemotherapy in the Treatment of Patients with Advanced Soft Tissue Sarcoma

S. Bauer, J. Hartung, T. Gauler, P. Gocke, T. Trarbach, M. Flasshove, M. R. Nowrousian, P. Bojko, J. Hense, S. Seeber, J. Schütte · TumorDiagnostik & Therapie · 2002 · Heft 06 · S. 219-224

Dokument
1099979
CareLit-ID
Jahr
2002
Publikation
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Bibliografische Angaben

Zeitschrift
TumorDiagnostik & Therapie
Autor:innen
S. Bauer, J. Hartung, T. Gauler, P. Gocke, T. Trarbach, M. Flasshove, M. R. Nowrousian, P. Bojko, J. Hense, S. Seeber, J. Schütte
Ausgabe
Heft 06 / 2002
Jahrgang 23
Seiten
219-224
Erschienen: 2002-01-01 00:00:00
ISSN
0722-219X
DOI
10.1055/s-2002-36487

Zusammenfassung

Abstract BACKGROUND: To assess the role of gemcitabine (G) or gemcitabine-containing regimens (GCR) in advanced soft tissue sarcoma (STS), we analyzed the response rate and the time-to-progression (TTP) in advanced STS patients (pts) following G/GCR treatment. PATIENTS AND METHODS: From 8/98 to 12/01, 38 pts were treated with G alone (N = 9), or GCR including docetaxel (N=14); cisplatin (N = 13); or vinorelbine or paclitaxel (N = 2). Histologies included advanced STS in 32 pts and gastrointestinal stromal tumors (GIST) in 6 pts. Thirty-three pts including 27 STS pts had been pre-treated with a median of two prio…

Schlagworte

Soft tissue sarcomas Gemcitabine Second-line therapy Third-line therapy Anthracyclines Cisplatin TumorDiagnostik & Therapie