CareLit Fachartikel

Bedeutung persistenter Organochlorverbindungen in der Pathogenese des Mammakarzinoms

M. Bauer, F. Hilpert, I. Meinhold-Heerlein, W. Jonat · Geburtshilfe und Frauenheilkunde · 2004 · Heft 07 · S. 681-689

Dokument
1100300
CareLit-ID
Jahr
2004
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
M. Bauer, F. Hilpert, I. Meinhold-Heerlein, W. Jonat
Ausgabe
Heft 07 / 2004
Jahrgang 64
Seiten
681-689
Erschienen: 2004-01-01 00:00:00
ISSN
0016-5751

Zusammenfassung

Abstract The role of persistent organochlorine compounds in the development of breast cancer is controversially discussed. Used as biocides or technical adjuvants for miscellaneous applications, organochlorines have been released into the environment for years. Due to their highly lipophilic properties, they have been able to accumulate in the food chain leading to a long lasting presence in human tissues. The evidence that organochlorines might be involved in the carcinogenesis of breast cancer is based on their complex toxicologic properties: organochlorines are able to influence estrogen-mediated and other en…

Schlagworte

Organochlorverbindungen polychlorierte Biphenyle Mammakarzinom Organochlorine compounds polychlorinated biphenyls breast cancer Breast Association Population Geburtshilfe und Frauenheilkunde