Burden of illness in patients with reflux disease – Evidence from a recent comparative methodological study in Hungary

The clinical and socioeconomic burden of gastro-esophageal reflux disease (GERD) is considerable. Aim: To describe the impact of heartburn on patients' Health-Related Quality of Life (HRQL) in Hungary. Method: Patients with symptoms of heartburn completed the Hungarian versions of the Gastrointestinal Symptom Rating Scale (GSRS), the Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD), the Short Form-36 (SF-36) and the Hospital Anxiety and Depression (HAD) scale. Frequency and severity of heartburn during the previous 7 days were also recorded. Results: 136 patients completed the assessments (mean age…