CareLit Fachartikel

20-Year Public Health Predictions for Chronic Hepatitis C-Related Morbidity and Mortality–A GEHMO Simulation

U Siebert, G Sroczynski, A Conrads-Frank, JB Wong, S Rossol · Zeitschrift für Gastroenterologie · 2004 · Heft 08

Dokument
1101265
CareLit-ID
Jahr
2004
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
U Siebert, G Sroczynski, A Conrads-Frank, JB Wong, S Rossol
Ausgabe
Heft 08 / 2004
Seiten
–
Erschienen: 2004-08-18 00:00:00
ISSN
0044-2771
DOI
10.1055/s-2004-831767

Zusammenfassung

Objective: To assess the public health impact of different antiviral therapies (AVT) for chronic hepatitis C (CHC) when accounting for CHC-related diseases (e.g., HIV/HCV co-infection, haemophilia, history of i.v. drug use). Methods: Design: We used a Markov model, the German Hepatitis C Model (GEHMO) [1], combined with with prevalence and incidence cohort simulation. Data Sources: Pooled efficacy data from clinical trials and literature-based epidemiologic data on CHC and co-morbidities. Target Population: All treatable treatment-naïve German patients with known CHC and elevated ALT levels. Time Horizon: 20 yea…

Schlagworte

Antivirale Therapie Chronische Hepatitis C Public Health Simulation Hepatitis Accounting Population After Zeitschrift für Gastroenterologie