Functional Connectivity between Cortex and Motor Nuclei of the Basal Ganglia across the Human Sleep-Wake Cycle
F Salih, P Grosse, A Sharott, R Khatami, T Trottenberg, GH Schneider, A Kupsch, P Brown · Klinische Neurophysiologie · 2004 · Heft 08
Bibliografische Angaben
Zusammenfassung
Functional imaging has shown a basal ganglia involvement in the activity changes across the human sleep-wake cycle. Here we used frequency analysis to explore whether motor nuclei of the basal ganglia (Globus pallidus internus [GPi], subthalamic nucleus [STN]) are functionally connected to the motor or the visual cortex in wakefulness, NREM2, NREM3/4 and REM sleep. To this end, we examined patients undergoing deep-brain stimulation for Parkinson's disease (PD; n=5) or dystonia (n=5). We simultaneously recorded local field potentials either from GPi or STN using a bipolar montage as well as scalp EEG (F3/4-C3/4,…