Pathological crying induced by deep brain stimulation
L Wojtecki, J Nickel, L Timmermann, M Maarouf, S Jörgens, M Südmeyer, F Schneider, R Seitz, J Voges, V Sturm, A Schnitzler · Aktuelle Neurologie · 2004 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an effective surgical treatment for Parkinson's Disease (PD) improving all cardinal motor symptoms by affecting striato-thalamic pathways to motor cortices. The STN is also known to be interconnected with limbic and prefrontal associative areas. Clinical observations of STN-DBS reported emotional effects like acute depression, acute episodes of laughter, relief from depression as well as changes in executive and memory functions. These findings have been characterised by analysis of stimulation pole localisation a…