In vitro model system for study of heptotoxicity

The hepatocells, as they perform the maintenance of homeostasis, are not always in direct contact with one another, but carry out a continuous communication. The chemical language of communication is maintained via various biological products, changes of cellcycle processes. Different agents, as halogenated hydrocarbones, induce the different biological processes on the liver, which can be the markers of these cells. Our aims were to investigate the effects of subtoxical doses chlorobenzenes on in vitro hepatocyte modells, obtained in various doses, and to compare their efficacy on the cellproliferation and cell…