Successful treatment of pyoderma gangrenosum, Crohn's disease and systemic lupus erythematosus with anti-TNF alpha blocker (infliximab) in a patient. Case report

Malignant pyoderma was developed in a middle-aged female patient, gradually spreading through out the whole body. Pyoderma affected the crooks of the body as well as both ears, as a rare manifestation and resulted in considerable pain. Local treatment with topical steroids and antibiotics did not result in any improvement. Based on her existing inflammatory bowel disease (Crohn's disease: CD) and also her clinical findings and histological test results pyoderma gangrenosum (PG) was diagnosed. The patient's clinical and immune serologic test results indicated systemic lupus erythematosus (SLE) as well. The therap…