Gilles de la Tourette's Syndrome – an update of drug treatment
L Regeur · Aktuelle Neurologie · 2005 · Heft 09
Bibliografische Angaben
Zusammenfassung
Gilles de la Tourette's syndrome (TS) is a neuropsychiatric disorder characterized by motor and vocal tics, and often associated with a variety of behavioral disturbances such as Obsessive-Compulsive Disorder (OCD) and Attention Deficit Hyperactivity Disorder (ADHD). Although the neurochemical pathology of TS is not fully known dysfunction of the basal ganglia with involvement of the central monoaminergic pathways is believed to be essential for the symptomatology.Other neurotransmitters like GABA, acetylcholine and opoids also seem to be involved. This has provided the rationale for drug treatment. Because of t…