PLACENTAL PERFUSION IN ONCOTIC TREATMENT OF SEVERE PREECLAMPSIA

Purpose: To evaluate placental perfusion (umbilical resistance index) in women with severe preeclampsia (SPE) on oncotic therapy. Methods and Materials: Twelve women with SPE and Htc >0.38 received oncotic therapy with dextran 40 (n=2) and 6% HAES with antihypertensive agents (n=10). Eight women had IUGR with oligohydramnios in addition to SPE. Antihypertensive therapy included nifedipine in nine, urapidil in two, and methyldopa in one patient. Umbilical resistance index (URI) was measured every other day during therapy on a Kretz Voluson 700 ultrasound device Results: A statistically significant decrease in URI…