Efficacy and safety of mitoxantrone in multiple sclerosis: a retrospective analysis of 105 patients
A Spichtinger, H Koch, U Baumgart, I Kleiter, P Pöschl, E Rothenfußer-Korber, R Zellner, U Bogdahn, A Steinbrecher · Aktuelle Neurologie · 2005 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: Several controlled trials have shown mitoxantrone (MIX) to be effective in relapsing-remitting and secondary progressive multiple sclerosis (RRMS, SPMS). The MS therapy consensus group has recommended the use of MIX for treatment escalation in patients with progressive RRMS and SPMS refractory to immunomodulatory drugs. In clinical practice it is often difficult to decide which patients will be likely to benefit from initiating MIX therapy. Objective: To assess safety and efficacy of MIX in the Regensburg cohort of MS patients. Methods: All consecutive 105 MS patients (age 35 + 8 years, 74 females) t…
