CareLit Fachartikel
Are prostaglandines involved in the sympathetic-nociceptive interaction in humans?
R Maag, J Schattschneider, I zum Buttel, A Binder, J Ludwig, G Wasner, R Baron · Aktuelle Neurologie · 2005 · Heft 10
Dokument
1102485
CareLit-ID
Jahr
2005
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
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Zusammenfassung
Aim of investigation: Iontophoresis of norepinephrine in capsaicin-treated skin is followed by an increase in spontaneous and evoked pains. It is unclear whether norepinephrine acts directly on adrenergic receptors located on nociceptive afferents or triggers prostaglandine release from sympathetic postganglionic terminals as suggested by animal studies. The effect of norepinephrine on capsaicin-induced pain prior and after inhibition of cyclooxygenase was studied. Methods: In 10 healthy subjects norepinephrine or placebo was iontophorised after topical application of capsaicin in the forearm. The effect of iont…
Schlagworte
Capsaicin
After
Acetylcholin
Deutschland
Blood
Aktuelle Neurologie
