CareLit Fachartikel
Paraneoplastic multifocal neuropathy with anti-CRMP5- and anti-amphiphysin antibodies and myositis preceeding recurrence of a small-cell bladder carcinoma
J Lewerenz, C Hagel, J Matschke, V.A Lennon, F Leypoldt · Aktuelle Neurologie · 2005 · Heft 10
Dokument
1102503
CareLit-ID
Jahr
2005
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Background: Paraneoplastic neurological syndromes occur as cross-reactivity of the tumor-directed immune response against nervous system structures. Antibodies against several nervous system proteins have been defined that are diagnostic for a paraneoplastic cause of neurological sequelae. The second most frequent antibody specificity seems to be anti-CRMP-5-immunoglobulin G, which is frequently associated with ANNA-1/anti-Hu-antibodies, the most frequent paraneoplastic antibody, or anti-calcium channel-antibodies. Small-cell lung carcinoma is found in the majority of patients with CRMP-5-antibodies. Only rarely…
Schlagworte
Antibodies
Biopsy
Antibody Specificity
Calcium
Breast
Tumor
Aktuelle Neurologie
