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Endogenous neural precursor cells display extensive tropism for experimental glioblastomas and improve survival in an animal model

R.G Glass, M.S Synowitz, G Kempermann, H.K Kettenmann · Aktuelle Neurologie · 2005 · Heft 10

Dokument
1102506
CareLit-ID
Jahr
2005
Publikation
PDF
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Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
R.G Glass, M.S Synowitz, G Kempermann, H.K Kettenmann
Ausgabe
Heft 10 / 2005
Seiten
–
Erschienen: 2005-10-26 00:00:00
ISSN
0302-4350

Zusammenfassung

Gliomas are the major tumour entity of the central nervous system. The term glioma implies that these cells may originate from glial cells, although this has not been proven. Recent evidence indicates an interaction and interrelationship of glioma cells with stem cells. Neural stem cells generate all neurons, astrocytes and oligodendrocytes of the developing brain. They persist through adulthood in two specialized stem cell niches. A number of recent studies suggest that altered proliferation and differentiation of neural stem and precursor cells could be the primary source for glioma. Previously, it was demonst…

Schlagworte

Tumor After Association Astrocytes Apoptosis Aged Aktuelle Neurologie