Short Tandem Repeat Polymorphisms in Esophageal Cancer Related Gene –2 are a Risk Faktor for Esophageal Adenocarcinoma
T Rawnaq, JT Kaifi, EF Yekebas, R Wachowiak, M Bubenheim, P Merkert, V Kalinin, JR Izbicki · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background: Recently presence of short tandem repeat (STR) polymorphisms in esophageal cancer related gene 2 (ECRG2; GenBank Accession Number AF268198) has been described to be a genetic risk marker for esophageal squamous cell carcinoma (ESCC) in China. In the present study we examined these STR polymorphisms in ECRG2 in Caucasian patients suffering from esophageal adenocarcinoma. Methods: The STR genotype TCA3/TCA3 was described to be a risk factor for ESCC in China. We retrospectively analyzed STR genotypes TCA3/TCA3, TCA3/TCA4 and TCA4/TCA4 in the noncoding region of exon 4 of the ECRG2 gene by using PCR fra…
