Detection of asymptomatic cerebral microbleeds on T2*-weighted gradient-echo MRI: A comparative study at 1.5 and 3 Tesla
C Stehling, C Oelschläger, S Orwat, S Kloska, S Kraemer, TU Niederstadt, I Nassenstein, HS Knecht, P Kirchhof, WL Heindel, R Bachmann · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2006 · Heft 07
Bibliografische Angaben
Zusammenfassung
Purpose: Cerebral microbleeds (CMBs) are frequently associated with small vessel disease, intracerebral haemorrhage, hypertension and lacunar stroke. They are mainly located in the deep and subcortical white matter. Gradient echo T2*-weighted MRI (T2*MRI) has a high sensitivity in detecting CMBs, due to its sensitivity to iron-induced susceptibility changes. On these images hemosiderin deposits in the perivascular space appear as small dot-like hypointense lesions. However, the magnitude of iron-induced susceptibility changes increases with the field strength, which should lead to a higher sensitivity for the de…